Ethyl Acetate → HCID 21961332, compound

HRID 272320Notes

Reaction equation

HRID 272320 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[C:12]3[C:13]([CH3:20])=[C:14]([NH2:19])[C:15]([CH3:18])=[C:16]([CH3:17])[C:11]=3[O:10][C:9]2([CH3:22])[CH3:21])=[CH:4][CH:3]=1.C([O:26][CH2:27][CH3:28])(=O)C>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[C:12]3[C:13]([CH3:20])=[C:14]([N:19]4[C:9](=[O:10])[C:8]5[C:28](=[CH:2][CH:3]=[CH:4][CH:5]=5)[C:27]4=[O:26])[C:15]([CH3:18])=[C:16]([CH3:17])[C:11]=3[O:10][C:9]2([CH3:22])[CH3:21])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 8857Ethyl AcetateHCID 10828013HCID 10828013, compound

Product 1

HCID 21961332HCID 21961332, compoundYield 72%

Procedure

By using 3-(4-fluorophenyl)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-amine, the title compound was synthesized according to Reference Example 35a. Yield: 72%. Melting point: 209-211° C. (Ethyl acetate)

Sources & evidence

ORD record
ord-4d9daae6c7e045c6ad7e7c91147e04d8
Source dataset
uspto-grants-2008_11
Patent number
US07456162B2

Reaction notes

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