HCID 21961362, compound → HCID 15516562, compound

HRID 272330Notes

Reaction equation

HRID 272330 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][C:10]=1[Cl:11])[C:7](=O)[N:6]([C:13]1[C:14]([CH3:33])=[C:15]([CH3:32])[C:16]3[O:20][C:19]([CH3:22])([CH3:21])[CH:18]([C:23]4[CH:28]=[CH:27][C:26]([F:29])=[CH:25][CH:24]=4)[C:17]=3[C:30]=1[CH3:31])[C:5]2=O>C(OCC)(=O)C>[Cl:11][C:10]1[CH:9]=[C:8]2[C:4](=[CH:3][C:2]=1[Cl:1])[CH2:5][N:6]([C:13]1[C:14]([CH3:33])=[C:15]([CH3:32])[C:16]3[O:20][C:19]([CH3:22])([CH3:21])[CH:18]([C:23]4[CH:28]=[CH:27][C:26]([F:29])=[CH:25][CH:24]=4)[C:17]=3[C:30]=1[CH3:31])[CH2:7]2

Participants

3

Reactant 1

HCID 21961362HCID 21961362, compound

Product 1

HCID 15516562HCID 15516562, compoundYield 25%

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

By using 5,6-dichloro-2-[3-(4-fluorophenyl)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl]-1H-isoindole-1,3(2H)-dione, the title compound was synthesized according to Example 2a. Yield: 25%. Melting point: 233-238° C. (Ethyl acetate)

Sources & evidence

ORD record
ord-ed38a6d8facf45e3a3fdf69032e07959
Source dataset
uspto-grants-2008_11
Patent number
US07456162B2

Reaction notes

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