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HRID27239

反应详情

EQUATION

反应方程式

HRID 27239 的结构方程式

REACTANTS

反应物

3
结构：c1ccncc1
HCID1049

Pyridine

C5H5N

结构：ClCl
HCID24526

Chlorine

Cl2

结构：C=C(C)[C@H](C(=O)OC(c1ccccc1)c1ccccc1)N1C(=O)[C@@H]2N=C(c3ccccc3)O[C@@H]21
HCID12911969

未命名化合物

PRODUCTS

生成物

1
结构：C=C(CCl)[C@H](C(=O)OC(c1ccccc1)c1ccccc1)N1C(=O)[C@@H]2N=C(c3ccccc3)O[C@@H]21
HCID56996092

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：ClC(Cl)(Cl)Cl
溶剂HCID5943

Carbon tetrachloride

CCl4

结构：CCOC(C)=O
溶剂HCID8857

Ethyl acetate

C4H8O2

PROCEDURE

实验过程

A solution of 100 mg of Compound (1a) in ethyl acetate is reacted with a solution (2.0 molar equivalents) of chlorine in carbon tetrachloride at room temperature. The obtained product is treated with 1.2 equivalents of pyridine for 45 minutes under ice cooling, instead of chromatography of silica gel, to yield 110 mg of Compound (7).