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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 272393Generated: October 31, 2026

4-Fluorobenzoyl chloride → 4-Fluoro-N-(2,4,6,7-tetramethyl-3-phenyl-5-benzofuranyl)benzamide

https://huagongshe.com/reaction/272393

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorobenzoyl chlorideHCID 67879—
ReactantHCID 68886540HCID 68886540—
SolventEthyl acetate hexaneHCID 21226206—
Product4-Fluoro-N-(2,4,6,7-tetramethyl-3-phenyl-5-benzofuranyl)benzamideHCID 1029357980%

Reaction Steps

By using 2,4,6,7-tetramethyl-3-phenyl-1-benzofuran-5-amine and 4-fluorobenzoyl chloride, the title compound was synthesized according to Example 1b. Yield: 80%. Melting point: 242-245° C. (Ethyl acetate-hexane).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07456162B2
Source datasetuspto-grants-2008_11
ORD IDord-0acc338a7cca4e4da9d2a44de9ab7e5c
Source noteuspto-grants-2008_11