Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Aripiprazole | HCID 60795 | — |
| Lösungsmittel | 1,2-Dichloroethane | HCID 11 | — |
| Produkt | Aripiprazole ethylenedichloride | HCID 11489682 | 136,5% |
Reaktionsschritte
Aripiprazole (3 gm) is mixed with ethylenedichloride (30 ml) and heated to 50° C. to form a clear solution. The solution is slowly cooled to 25° C., stirred for 1 hour at about 25° C. and the separated crystals are collected by filtration to give 2.5 gm of aripiprazole ethylenedichloride solvate form V.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US07456181B2 |
|---|
| Quelldatensatz | uspto-grants-2008_11 |
|---|
| ORD ID | ord-96181f3c68c34f33896c55e67d1d75aa |
|---|
| Quellennotiz | uspto-grants-2008_11 |
|---|
