反应详情

温度

50 °C

Aripiprazole (3 gm) is mixed with ethylenedichloride (30 ml) and heated to 50° C. to form a clear solution. The solution is slowly cooled to 25° C., stirred for 1 hour at about 25° C. and the separated crystals are collected by filtration to give 2.5 gm of aripiprazole ethylenedichloride solvate form V.

1. customto form a clear solution
2. temperatureThe solution is slowly cooled to 25° C.
3. filtrationthe separated crystals are collected by filtration