HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Cyanobenzenesulfonyl Chloride → HCID 69109528, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Cyanobenzenesulfonyl Chloride | HCID 522347 | — |
| Reactant | 4,4-Difluoropiperidine | HCID 2758352 | — |
| Product | HCID 69109528 | HCID 69109528 | 24.9% |
Reaction Steps
(2-(4,4-Difluoropiperidin-1-ylsulfonyl)phenyl)methanamine hydrochloride (81 mg) was prepared in two steps from commercially available 2-cyanobenzene-1-sulfonyl chloride (201 mg) and 4,4-difluoropiperidine (316 mg) in 25% overall yield following a procedure analogous to that used in the preparation 210A. LC-MS: 291.19 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07456195B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-e5b7d88b2cc04c6b9990e5ce6b4a2b66 |
| Source note | uspto-grants-2008_11 |