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HRID273001

反应详情

EQUATION

反应方程式

HRID 273001 的结构方程式

REACTANTS

反应物

3
结构：CN1CCNCC1
HCID53167

1-Methylpiperazine

C5H12N2

结构：COc1ccc(C2(C(=O)O)CCOCC2)cc1
HCID969802

4-(4-methoxyphenyl)tetrahydro-2H-pyran-4-carboxylic acid

C13H16O4

结构：CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F
HCID2733207

O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate

C11H16BF4N5O

PRODUCTS

生成物

1
结构：COc1ccc(C2(C(=O)N3CCN(C)CC3)CCOCC2)cc1
HCID16415282

(4-Methyl-1-piperazinyl)[tetrahydro-4-(4-methoxyphenyl)-2H-pyran-4-yl]methanone

C18H26N2O3

收率 77%

PROCEDURE

实验过程

The title compound (515 mg, 77%) was prepared using 4-(4-methoxyphenyl)tetrahydro-2H-pyran-4-carboxylic acid, N-methyl-piperazine and O-(1H-benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate (TBTU) similarly to the procedure used for example 166. HRMS ESI+ m/z 319.2009 [MH]+.