HuagongsheHuagongshe Chemistry Print Report · For research reference only
[4-(4-Methoxyphenyl)oxan-4-yl]-morpholin-4-ylmethanone → 4-{[4-(4-methoxyphenyl)tetrahydro-2H-pyran-4-yl]methyl}-morpholine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [4-(4-Methoxyphenyl)oxan-4-yl]-morpholin-4-ylmethanone | HCID 976657 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Product | 4-{[4-(4-methoxyphenyl)tetrahydro-2H-pyran-4-yl]methyl}-morpholine | HCID 68575527 | 87% |
Reaction Steps
The title compound (2.48 g, 87%) was prepared using 4-{[4-(4-methoxyphenyl)tetrahydro-2H-pyran-4-yl]carbonyl}morpholine and lithium aluminium hydride similarly to the procedure used for example 142. HRMS ESI+ m/z 292.1897 [MH]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07456164B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-706cc26355d041189cc3dc50b2b1dcc2 |
| Source note | uspto-grants-2008_11 |