反应详情

To 30 ml. of dihdropyran containing 450 mg. of p-toluenesulfonyl chloride was added 6.0 g. of the product of Step B and the solution was stirred at room temperature for 1 hr. The solution was then diluted with ethyl ether and washed with a 20% pyridine water mixture twice, and then water, then brine, and dried and evaporated to yield a pale yellow oil which crystallized (8.5 g.), and had a m.p. of 92°-96° C.

1. additionof dihdropyran containing 450 mg
2. washwashed with a 20% pyridine water mixture twice
3. dry with materialwater, then brine, and dried
4. customevaporated
5. customto yield a pale yellow oil which
6. customcrystallized (8.5 g.)