HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dioxane → Methyl 2-(6-methoxybenzofuran-3-yl)-2-oxoacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | Methyl 2-(6-methoxy-1-benzofuran-3-yl)acetate | HCID 15618717 | — |
| Product | Methyl 2-(6-methoxybenzofuran-3-yl)-2-oxoacetate | HCID 69194602 | 85% |
Reaction Steps
A mixture of methyl 2-(6-methoxybenzofuran-3-yl)acetate (0.500 g, 2.27 mmol) and SeO2 (0.303 g, 2.73 mmol) in 1,4-dioxane (10 mL) was refluxed for 2 days and then filtered. The filtrate was concentrated in vacuo and the residue was purified on a silica gel column to give methyl 2-(6-methoxybenzofuran-3-yl)-2-oxoacetate (0.452 g, 85%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07456289B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-8db19c826ac844ec9f6887842b460143 |
| Source note | uspto-grants-2008_11 |