HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 58903145, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 58903179 | HCID 58903179 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 58903145 | HCID 58903145 | 72.1% |
Reaction Steps
To a solution of tert-butyl 3-[4-({4′-[2-(ethylsulfonyl)ethoxy]-2′,6′-dimethylbiphenyl-3-yl}methoxy)phenyl]propanoate (0.37 g, 0.67 mmol) in toluene (3.7 mL) was added trifluoroacetic acid (3.7 mL) at room temperature with stirring and the mixture was stirred at room temperature for 2 hrs. The reaction mixture was concentrated under reduced pressure, the obtained crystals were collected by filtration, washed and dried to give the title compound (0.24 g, yield 72%) as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07456218B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-97eed43bc92d487fa398a8904d4361cf |
| Source note | uspto-grants-2008_11 |