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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 273410Generated: October 31, 2026

Trifluoroacetic acid → HCID 58903145, compound

https://huagongshe.com/reaction/273410

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 58903179HCID 58903179—
SolventTolueneHCID 1140—
ProductHCID 58903145HCID 5890314572.1%

Reaction Steps

To a solution of tert-butyl 3-[4-({4′-[2-(ethylsulfonyl)ethoxy]-2′,6′-dimethylbiphenyl-3-yl}methoxy)phenyl]propanoate (0.37 g, 0.67 mmol) in toluene (3.7 mL) was added trifluoroacetic acid (3.7 mL) at room temperature with stirring and the mixture was stirred at room temperature for 2 hrs. The reaction mixture was concentrated under reduced pressure, the obtained crystals were collected by filtration, washed and dried to give the title compound (0.24 g, yield 72%) as colorless crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07456218B2
Source datasetuspto-grants-2008_11
ORD IDord-97eed43bc92d487fa398a8904d4361cf
Source noteuspto-grants-2008_11