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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 273411Generated: November 1, 2026

Hydrogen chloride-ethyl acetate → HCID 69316376, compound

https://huagongshe.com/reaction/273411

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrogen chloride-ethyl acetateHCID 21866389—
ReactantHCID 58903100HCID 58903100—
SolventEthyl AcetateHCID 8857—
ProductHCID 69316376HCID 6931637671%

Reaction Steps

To a solution of 3-[4-({2′,6′-dimethyl-4′-[3-(6-methylpyridin-2-yl)propoxy]biphenyl-3-yl}methoxy)phenyl]propanoic acid (55 mg, 0.11 mmol) in ethyl acetate (2.2 mL) was added 4 N hydrogen chloride-ethyl acetate solution (81 μL, 0.32 mmol) and the mixture was concentrated under reduced pressure. The obtained crystals were collected by filtration, washed and dried to give the title compound (42 mg, yield 71%) as colorless crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07456218B2
Source datasetuspto-grants-2008_11
ORD IDord-8b1e23642cf14fea9d4ae9cd7a19537b
Source noteuspto-grants-2008_11