HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Piperidinecarboxylic acid → 1-Acetylpiperidine-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Piperidinecarboxylic acid | HCID 3773 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Product | 1-Acetylpiperidine-4-carboxylic acid | HCID 117255 | — |
Reaction Steps
1-Acetylpiperidine-4-carboxylic acid is prepared by bringing a solution of piperidine-4-carboxylic acid in acetic anhydride to reflux for 2 hours and then stirring for 16 hours at room temperature. The solution is then concentrated and the residue is triturated in ether. The solid compound is recovered by filtration.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05387586 |
| Source dataset | uspto-grants-1995_02 |
| ORD ID | ord-90f4bb99ebd4472094cdb311170e5dc3 |
| Source note | uspto-grants-1995_02 |