反应详情

34 g of 2,2'-methylenebis(6-tert-butyl-4-methylphenol) was dissolved in 50 ml of acetone and 27.6 g of anhydrous calcium chloride was added to this solution. 15 g of methyl iodide was slowly added dropwise thereto while stirring under reflux. After stirring for 6 hours, the reaction mixture was cooled and solid matter was filtered off. The filtrate was poured into ice-water and the formed crystals were filtered off. The crystals were recrystallized from water-containing methanol to obtain 28.2 g of compound (59).

1. temperatureunder reflux
2. stirringAfter stirring for 6 hours
3. temperaturethe reaction mixture was cooled
4. filtrationsolid matter was filtered off
5. additionThe filtrate was poured into ice-water
6. filtrationthe formed crystals were filtered off
7. customThe crystals were recrystallized from water-
8. additioncontaining methanol