Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | HCID 23342878 | HCID 23342878 | — |
| Product | HCID 23342866 | HCID 23342866 | 82% |
Reaction Steps
5.07 g (0,03 mol) of 1-(tetrahydro-2-oxo-3-furyl)-2-pyrrolidinone are mixed with 10.45 g (0.12 mol) of morpholine and the reaction mixture is heated at 110° C. for 5 hours. Upon cooling, the product crystallizes. The product is filtered and recrystallized from diethyl ether. 6.3 g (yield: 82% of theory) of 4-[4-hydroxy-2-(2-oxo-1-pyrrolidinyl)butyryl]-morpholine are obtained. M.P.: 105°-106° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04221789 |
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| Source dataset | uspto-grants-1980_09 |
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| ORD ID | ord-998d1067ea0c4e829ca7f57386e40294 |
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| Source note | uspto-grants-1980_09 |
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