反应详情

温度

50 °C

467.3 g of 2-cyano-4'-methylbiphenyl, prepared above, are dissolved in 4.7 l of 1,2-dichloroethane in the presence of 467.3 g of N-bromosuccinimide and 9.3 g of benzoyl peroxide. The mixture is heated very gradually so as to have good control over the exothermic effect. It is subsequently refluxed for 4 h, cooled to 50° C. and then washed 3 times with hot water and dried and the organic phase is concentrated to give cream-colored crystals.

1. temperatureThe mixture is heated very gradually so as
2. temperatureIt is subsequently refluxed for 4 h
3. washwashed 3 times with hot water
4. customdried
5. concentrationthe organic phase is concentrated
6. customto give cream-colored crystals