Triethyl phosphite → ethyl 2-(5-methyl-2H-indazol-2-yl)benzoate

참여 물질

반응 단계

Triethyl phosphite (5.8 ml, 34 mmol) was added to ethyl N-(5-methyl-2-nitrobenzylidene)anthranilate (3.10 g, 9.93 mmol) as obtained in Reference Example 2. The mixture was refluxed under heating for 4 hours, and the triethyl phosphite was evaporated under reduced pressure. The residue was purified by flash chromatography on silica gel using a mixed solvent of hexane/ethyl acetate (5:1), whereby 1.79 g of ethyl 2-(5-methyl-2H-indazol-2-yl)benzoate was obtained.

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