Chlorosuccinimide → HCID 20094523, compound

HRID 274145Notes

Reaction equation

[CH3:1][C:2]1[CH:10]=[CH:9][C:8]2[C:4](=[CH:5][N:6]([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=3[C:17]3[N:18]=[N:19][N:20]([C:22]([C:35]4[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=4)([C:29]4[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=4)[C:23]4[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=4)[N:21]=3)[N:7]=2)[CH:3]=1.[Cl:41]N1C(=O)CCC1=O>>[Cl:41][C:5]1[N:6]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[C:17]2[N:18]=[N:19][N:20]([C:22]([C:35]3[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=3)([C:29]3[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=3)[C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)[N:21]=2)[N:7]=[C:8]2[C:4]=1[CH:3]=[C:2]([CH3:1])[CH:10]=[CH:9]2

Participants

Reactant 2

HCID 31398Chlorosuccinimide

HCID 20094546HCID 20094546, compound

Product 1

HCID 20094523HCID 20094523, compound

Procedure

By treating 5-[2-(5-methyl-2H-indazol-2-yl)phenyl]-2-(triphenylmethyl)-2H-tetrazole as obtained in Reference Example 8, in the same manner as in Reference Example 4 by using N-chlorosuccinimide (1 equivalent amount) in place of N-bromosuccinimide, 5-[2-(3-chloro-5-methyl-2H-indazol-2-yl)-phenyl]-2-(triphenylmethyl)-2H-tetrazole was obtained.

Workup

customas obtained in Reference Example 8, in the same manner as in Reference Example 4

Sources & evidence

ORD record: ord-ea045bd5fa47421db4a47245ba57cbf1
Source dataset: uspto-grants-1995_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05387684

Reaction notes

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