1-(4-Ethoxyphenyl)-2-(4'-difluoromethoxyphenyl)-ethene → 1-(4-Ethoxyphenyl)-2-(4'-difluoromethoxyphenyl)-ethane
Reaction equation
[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([CH:10]=[CH:11][C:12]2[CH:17]=[CH:16][C:15]([O:18][CH:19]([F:21])[F:20])=[CH:14][CH:13]=2)=[CH:6][CH:5]=1)[CH3:2]>C1COCC1.[Pd]>[CH2:1]([O:3][C:4]1[CH:5]=[CH:6][C:7]([CH2:10][CH2:11][C:12]2[CH:17]=[CH:16][C:15]([O:18][CH:19]([F:20])[F:21])=[CH:14][CH:13]=2)=[CH:8][CH:9]=1)[CH3:2]Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
19.7 g of 1-(4-ethoxyphenyl)-2-(4'-difluoromethoxyphenyl)-ethene are hydrogenated in 150 ml of THF analogously to Example 6b, using 6 g of Pd/C (5% Pd) as catalyst. m.p.: 37° C., Δn=0.103, viscosity: 8
Sources & evidence
- ORD record
- ord-431f2111be454c3390d72201fb8bfb6a
- Source dataset
- uspto-grants-1995_02
- Patent number
- US05389292
Reaction notes
Loading…