2-Fluoro-6-phenylsulfonylpyridine → HCID 17911500, compound

Participants

Reaction Steps

A mixture of 0.06 mol of 4-octyloxyphenylmagnesium bromide (prepared from 0.06 mol of 4-octyloxybromobenzene and 0.06 mol of 4-octyloxybromobenzene and 0.06 mol of magnesium) and 25 ml of THF is added at 30°-40° C. to a mixture of 0.05 mol of 2A and 15 ml of THF. The mixture is stirred at room temperature for 2 hours and subjected to customary work-up. The unpurified product is processed further in accordance with 2C.

Provenance & Evidence