反应详情

A solution of phenylsuccinic acid (20.0 g, 0.10 mol), acetyl chloride, and 200 mL of toluene was stirred at reflux for 5.5 hours, removing H2O azeotropically during the reaction. After cooling to room temperature, toluene was evaporated in vacuo, and the residue was crystallized from ether to obtain 12.2 g of phenyl succinic anhydride as a white solid.

1. temperatureat reflux for 5.5 hours
2. customremoving H2O
3. customazeotropically during the reaction
4. customtoluene was evaporated in vacuo
5. customthe residue was crystallized from ether