HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → Phenylsuccinic Anhydride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | Phenylsuccinic acid | HCID 95459 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | Phenylsuccinic Anhydride | HCID 136911 | 69.3% |
Reaction Steps
A solution of phenylsuccinic acid (20.0 g, 0.10 mol), acetyl chloride, and 200 mL of toluene was stirred at reflux for 5.5 hours, removing H2O azeotropically during the reaction. After cooling to room temperature, toluene was evaporated in vacuo, and the residue was crystallized from ether to obtain 12.2 g of phenyl succinic anhydride as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05389638 |
| Source dataset | uspto-grants-1995_02 |
| ORD ID | ord-e75f300991c6444c9374936561666c4b |
| Source note | uspto-grants-1995_02 |