Hydrogen Bromide → 3,4-Dihydroxy-5-nitrophenyl 3-pyridyl ketone hydrobromide

HRID 274436Notes

Reaction equation

HRID 274436 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]([C:9]2[CH:14]=[C:13]([N+:15]([O-:17])=[O:16])[C:12]([OH:18])=[C:11]([O:19]C)[CH:10]=2)=[O:8])[CH:2]=1.[BrH:21]>>[BrH:21].[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]([C:9]2[CH:14]=[C:13]([N+:15]([O-:17])=[O:16])[C:12]([OH:18])=[C:11]([OH:19])[CH:10]=2)=[O:8])[CH:2]=1

Participants

3

Reactant 2

HCID 260Hydrogen BromideHCID 214591634-Hydroxy-3-methoxy-5-nitrophenyl 3-pyridyl ketone

Product 1

HCID 214590113,4-Dihydroxy-5-nitrophenyl 3-pyridyl ketone hydrobromide

Procedure

3.5 g of 4-hydroxy-3-methoxy-5-nitrophenyl 3-pyridyl ketone dissolved in 70 ml of 48 percent aqueous hydrobromic acid are stirred at 100° for 18 hours. The reaction mixture is subsequently evaporated under reduced pressure. The residue is recrystallized from water. There is obtained 3,4-dihydroxy-5-nitrophenyl 3-pyridyl ketone hydrobromide of m.p. 265°.

Workup

  1. customThe reaction mixture is subsequently evaporated under reduced pressure
  2. customThe residue is recrystallized from water

Sources & evidence

ORD record
ord-f8c7695ad7f44f09a226e4a7b0fd3d4a
Source dataset
uspto-grants-1995_02
Patent number
US05389653

Reaction notes

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