HuagongsheHuagongshe Chemistry Print Report · For research reference only
alpha-(3,4-Dimethoxy-5-nitrophenyl)-2-thiophenemethanol → 3,4-Dimethoxy-5-nitrophenyl 2-thienyl ketone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | alpha-(3,4-Dimethoxy-5-nitrophenyl)-2-thiophenemethanol | HCID 21458951 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 3,4-Dimethoxy-5-nitrophenyl 2-thienyl ketone | HCID 17977694 | — |
Reaction Steps
9.9 g of α-(3,4-dimethoxy-5-nitrophenyl)-2-thiophenemethanol dissolved in 300 ml of acetone are treated with 90 g of manganese dioxide and heated under reflux for 4 hours. The manganese dioxide is removed by suction filtration and the filtrate is evaporated. There is obtained 3,4-dimethoxy-5-nitrophenyl 2-thienyl ketone of m.p. 102°-104° (from methylene chloride/hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05389653 |
| Source dataset | uspto-grants-1995_02 |
| ORD ID | ord-e43290f302cc4971ba54ee9b80d84760 |
| Source note | uspto-grants-1995_02 |