Ammonia → HCID 15239086, compound

HRID 274732Notes

Reaction equation

HRID 274732 reaction equation
ClC(Cl)(Cl)[C:3]([C:5]1[NH:6][CH:7]=[C:8]([C:10]#[N:11])[CH:9]=1)=[O:4].[NH3:14]>CO.O>[C:10]([C:8]1[CH:9]=[C:5]([C:3]([NH2:14])=[O:4])[NH:6][CH:7]=1)#[N:11]

Participants

5

Reactant 2

HCID 222AmmoniaHCID 127304765-(Trichloroacetyl)-1H-pyrrole-3-carbonitrile

Product 1

HCID 15239086HCID 15239086, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent

Procedure

A solution of 2-trichloroacetylpyrrole-4-carbonitrile (20 g, 84.2 mmol) in methanol is treated with ammonia (51 mL), stirred at room temperature for 30 minutes and diluted with water. The aqueous mixture is filtered to obtain the title product as a white solid (7.0 g, mp 253°-256° C.).

Workup

  1. filtrationThe aqueous mixture is filtered

Sources & evidence

ORD record
ord-d13606e42b364f86abc512497f317646
Source dataset
uspto-grants-1995_02
Patent number
US05389669

Reaction notes

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