HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 15239086, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 5-(Trichloroacetyl)-1H-pyrrole-3-carbonitrile | HCID 12730476 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 15239086 | HCID 15239086 | — |
Reaction Steps
A solution of 2-trichloroacetylpyrrole-4-carbonitrile (20 g, 84.2 mmol) in methanol is treated with ammonia (51 mL), stirred at room temperature for 30 minutes and diluted with water. The aqueous mixture is filtered to obtain the title product as a white solid (7.0 g, mp 253°-256° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05389669 |
| Source dataset | uspto-grants-1995_02 |
| ORD ID | ord-d13606e42b364f86abc512497f317646 |
| Source note | uspto-grants-1995_02 |