HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dipropylamine → 8-Bromo-2-dipropylamino-1,2,3,4-tetrahydronaphthalene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dipropylamine | HCID 8902 | — |
| Reactant | 8-Bromo-1,2,3,4-tetrahydronaphthalen-2-one | HCID 4136187 | — |
| Reactant | Sodium cyanoborohydride | HCID 5003444 | — |
| Product | 8-Bromo-2-dipropylamino-1,2,3,4-tetrahydronaphthalene | HCID 14529564 | — |
Reaction Steps
8-Bromo-2-tetralone (28.8 gm, 128 mMol) was reacted with dipropylamine (34.3 mL, 250 mMol) and sodium cyanoborohydride (6.3 gm, 100 mMol) as described in Example 3 to give the title compound as a light yellow oil. The hydrochloride salt was formed and crystallization (acetone) gave colorless crystals (m.p.=150.5°-152° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05389687 |
| Source dataset | uspto-grants-1995_02 |
| ORD ID | ord-b936a313be9242deb7fe486dfe0f11ac |
| Source note | uspto-grants-1995_02 |