HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dipropylamine → 7-(Dipropylamino)-5,6,7,8-tetrahydronaphthalene-1-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dipropylamine | HCID 8902 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | HCID 15230502 | HCID 15230502 | — |
| Product | 7-(Dipropylamino)-5,6,7,8-tetrahydronaphthalene-1-carbonitrile | HCID 10060986 | — |
Reaction Steps
8-Cyano-2-tetralone (500 mg, 2.9 mMol) was reacted with dipropylamine (0.8 mL, 5.8 mMol) and sodium borohydride (370 mg) as described in Example 1 to give the title compound as a colorless, viscous oil (260 mg, 35%). The hydrochloride salt was formed and crystallization (ethanol/diethyl ether) gave colorless crystals (m.p.=175°-176° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05389687 |
| Source dataset | uspto-grants-1995_02 |
| ORD ID | ord-6a425c85dcc34025aefd111b37534e5a |
| Source note | uspto-grants-1995_02 |