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HRID274848

反应详情

EQUATION

反应方程式

HRID 274848 的结构方程式

REACTANTS

反应物

3
反应SMILES：COS(=O)(=O)OC
HCID6497

Dimethyl sulfate

C2H6O4S

反应SMILES：O=C([O-])[O-].[K+].[K+]
HCID11430

Potassium Carbonate

CK2O3

反应SMILES：O=c1cc(C(F)(F)F)[nH]c(=O)n1Cc1cc([N+](=O)[O-])cc(Cl)c1Cl
HCID21478104

未命名化合物

PRODUCTS

产物

1
反应SMILES：Cn1c(C(F)(F)F)cc(=O)n(Cc2cc([N+](=O)[O-])cc(Cl)c2Cl)c1=O
HCID21478127

未命名化合物

收率 20.8%

AUXILIARIES

试剂、催化剂与溶剂

1
反应SMILES：CC(C)=O
溶剂HCID180

Acetone

C3H6O

PROCEDURE

实验过程

By the method of Example 1, Step H, 24.5 grams (0.064 mole) of 3-(2,3-dichloro-5-nitrophenylmethyl)-6-trifluoromethyluracil, 12.07 grams (0.096 mole) of dimethyl sulfate, and 17.64 grams (0.127 mole) of potassium carbonate were reacted in 300 mL of acetone, yielding 5.30 grams of 3-(2,3-dichloro-5-nitrophenylmethyl)-1-methyl-6-trifluoromethyluracil as a bright yellow solid. The NMR spectrum was consistent with the proposed structure.