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HRID274897

反应详情

EQUATION

反应方程式

HRID 274897 的结构方程式

REACTANTS

反应物

1
结构：OC1(c2ccc(F)c(F)c2)CCC2(CC1)OCCO2
HCID22122104

未命名化合物

PRODUCTS

生成物

1
结构：O=C1CCC(O)(c2ccc(F)c(F)c2)CC1
HCID22122090

未命名化合物

收率 62%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)=O
溶剂HCID180

Acetone

C3H6O

PROCEDURE

实验过程

A solution of 8-(3,4-difluorophenyl)-1,4-dioxaspiro[4.5]decan-8-ol (5.4 g, 20 mmole) in acetone-1N hydrochloric acid (1:1) was stirred for 4 hr. The acetone was removed in vacuo and the crude material crystallized from isopropyl ether to give the product (62%, mp: 84°-85 ° C.).

WORKUP

后处理

  1. customThe acetone was removed in vacuo
  2. customthe crude material crystallized from isopropyl ether