反应详情

温度

50 °C

To a suspension of 4.85 g (10.9 mMol) of N-trifluoroacetyl-4-acetylamino-3-nitro-phenylalanyl-(4-methyl-piperidine) in 10 ml of ethanol 28.0 ml of 1N sodium hydroxide solution are added dropwise at 20° C. After 3 hours' stirring at 50° C. the mixture is cooled, then after another 2 hours it is suction filtered and washed with a little ice water.

1. additionare added dropwise at 20° C
2. temperatureis cooled
3. waitafter another 2 hours it is
4. filtrationsuction filtered
5. washwashed with a little ice water