HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 274956Generated: October 25, 2026
Sodium Hydroxide → 4-Amino-3-nitro-phenylalanyl-(4-methyl-piperidine)
https://huagongshe.com/reaction/274956
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | N-trifluoroacetyl-4-acetylamino-3-nitro-phenylalanyl-(4-methyl-piperidine) | HCID 18659294 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-Amino-3-nitro-phenylalanyl-(4-methyl-piperidine) | HCID 18659293 | — |
Reaction Steps
To a suspension of 4.85 g (10.9 mMol) of N-trifluoroacetyl-4-acetylamino-3-nitro-phenylalanyl-(4-methyl-piperidine) in 10 ml of ethanol 28.0 ml of 1N sodium hydroxide solution are added dropwise at 20° C. After 3 hours' stirring at 50° C. the mixture is cooled, then after another 2 hours it is suction filtered and washed with a little ice water.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05391556 |
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| Source dataset | uspto-grants-1995_02 |
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| ORD ID | ord-05decc9ee9b645bfa1b64e77eb31c1d3 |
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| Source note | uspto-grants-1995_02 |
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