Hydrochloric Acid → HCID 178428635, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 0.6 g (0.001 Mol) of ethyl [3-[[1-(1H-benzimidazol-5-yl-methyl)-2-(4-methyl-piperidin-1-yl)-2-oxo-ethyl]sulphamoyl]-carbazol-9-yl]-acetate in 5 ml of dioxane and 5 ml of methanol are added dropwise 4 ml of 1N sodium hydroxide solution and the mixture is stirred at 20° C. for one hour. It is then diluted with 20 ml of water and mixed with 4 ml of 1N hydrochloric acid. The organic solvent is eliminated in vacuo, the product precipitated is suction filtered, washed with water and dried.

Provenance & Evidence