HRID274977

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC1CCN(C(=O)C(Cc2ccc3[nH]cnc3c2)NS(=O)(=O)c2ccc(-c3ccccc3[N+](=O)[O-])cc2)CC1

HCID178428643

未命名化合物

PRODUCTS

生成物

结构：CC1CCN(C(=O)C(Cc2ccc3[nH]cnc3c2)NS(=O)(=O)c2ccc(-c3ccccc3N)cc2)CC1

HCID178428642

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID935

Nickel

催化剂HCID23939

Platinum

PROCEDURE

实验过程

Prepared from N-[1-(1H-benzimidazol-5-yl-methyl)-2-(4-methyl-piperidin-1-yl)-2-oxo-ethyl]-2'-nitro-4-biphenylyl-sulphonamide in the presence of platinum/charcoal or Raney nickel and under a hydrogen pressure of 3 bar analogously to Example 22.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-b22f0c97e8a74c22b1e2670f7868c452
来源数据集: uspto-grants-1995_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05391556
来源说明: uspto-grants-1995_02

反应 SMILES

[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH2:10][CH:11]([NH:21][S:22]([C:25]3[CH:30]=[CH:29][C:28]([C:31]4[CH:36]=[CH:35][CH:34]=[CH:33][C:32]=4[N+:37]([O-])=O)=[CH:27][CH:26]=3)(=[O:24])=[O:23])[C:12]([N:14]3[CH2:19][CH2:18][CH:17]([CH3:20])[CH2:16][CH2:15]3)=[O:13])=[CH:9][C:4]=2[N:3]=[CH:2]1>[Ni].[Pt]>[NH:1]1[C:5]2[CH:6]=[CH:7][C:8]([CH2:10][CH:11]([NH:21][S:22]([C:25]3[CH:26]=[CH:27][C:28]([C:31]4[CH:36]=[CH:35][CH:34]=[CH:33][C:32]=4[NH2:37])=[CH:29][CH:30]=3)(=[O:23])=[O:24])[C:12]([N:14]3[CH2:19][CH2:18][CH:17]([CH3:20])[CH2:16][CH2:15]3)=[O:13])=[CH:9][C:4]=2[N:3]=[CH:2]1