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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 27501Generated: October 26, 2026

Ethylenediamine → HCID 178484971, compound

https://huagongshe.com/reaction/27501

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylenediamineHCID 3301—
Reactant1-Cyano-2,3-dimethylisothioureaHCID 111103—
Reactant5-(Bromomethyl)-1H-pyrazoleHCID 178419514—
ReactantHCID 178511340HCID 178511340—
ProductHCID 178484971HCID 178484971—

Reaction Steps

Reacting 3-bromomethylpyrazole with ethylenediamine by the procedure of Example 34 and reacting the resulting N-(3-pyrazolylmethyl)ethylenediamine with N-cyano-N',S-dimethylisothiourea by the procedure of Example 3(d) gives N-cyano-N'-methyl-N"-[2-(3-pyrazolylmethylamino)ethyl]guanidine. Hydrolysis of this compound by the procedure of Example 3(e) gives N-methyl-N'-[2-(3-pyrazolylmethylamino)ethyl]guanidine trihydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04221802
Source datasetuspto-grants-1980_09
ORD IDord-d926bcb70309478bb2c38f6c76e10893
Source noteuspto-grants-1980_09