反应详情

A mixture of 3.5 g (10 mmol) of 5-formylamino-N-(2,6-dichloro-3-methylphenyl)-1,2,4-triazole-3-sulfonamide and 50 ml of 1 percent aqueous sodium hydroxide was heated to reflux for 4 hours and was then cooled and acidified with dilute aqueous hydrochloric acid. The solids that formed were collected by filtration and dried to obtain 2.77 g (86 percent of theory) of the title compound, m.p. 243°-44° C. The proton and carbon nmr spectra were consistent with the assigned structure.

1. temperaturewas heated
2. temperatureto reflux for 4 hours
3. temperaturewas then cooled
4. customThe solids that formed
5. filtrationwere collected by filtration
6. customdried