Hydrochloric Acid → HCID 178425411, compound

HRID 275041Notes

Reaction equation

HRID 275041 reaction equation
C([NH:3][C:4]1[NH:8][N:7]=[C:6]([S:9]([NH:12][C:13]2[C:18]([Cl:19])=[CH:17][CH:16]=[C:15]([CH3:20])[C:14]=2[Cl:21])(=[O:11])=[O:10])[N:5]=1)=O.Cl>[OH-].[Na+]>[NH2:3][C:4]1[NH:8][N:7]=[C:6]([S:9]([NH:12][C:13]2[C:18]([Cl:19])=[CH:17][CH:16]=[C:15]([CH3:20])[C:14]=2[Cl:21])(=[O:11])=[O:10])[N:5]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 1784254105-formylamino-N-(2,6-dichloro-3-methylphenyl)-1,2,4-triazole-3-sulfonamide

Product 1

HCID 178425411HCID 178425411, compound

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

A mixture of 3.5 g (10 mmol) of 5-formylamino-N-(2,6-dichloro-3-methylphenyl)-1,2,4-triazole-3-sulfonamide and 50 ml of 1 percent aqueous sodium hydroxide was heated to reflux for 4 hours and was then cooled and acidified with dilute aqueous hydrochloric acid. The solids that formed were collected by filtration and dried to obtain 2.77 g (86 percent of theory) of the title compound, m.p. 243°-44° C. The proton and carbon nmr spectra were consistent with the assigned structure.

Workup

  1. temperaturewas heated
  2. temperatureto reflux for 4 hours
  3. temperaturewas then cooled
  4. customThe solids that formed
  5. filtrationwere collected by filtration
  6. customdried

Sources & evidence

ORD record
ord-c0aecce82ba04da9acfed622be2c5a71
Source dataset
uspto-grants-1995_02
Patent number
US05391759

Reaction notes

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