反应详情

20 g (72.4 mmol) of 2-fluoro-naphthacene-5,12-dione, 94.3 g of 1-octanol, 30.01 g (217.2 mmol) of anhydrous potassium carbonate and 200 ml of dimethyl sulfoxide (DMSO) are stirred at a bath temperature of 100° C. for 20 hours. The reaction mixture is cooled, toluene/dilute hydrochloric acid are added and the organic phase is separated off, washed twice with water, dried with sodium sulfate and evaporated. The residue is washed with pentane and recrystallized from cyclohexane. Yield: 22.9 g (82%), melting point 127°-129° C.

1. temperatureThe reaction mixture is cooled
2. customthe organic phase is separated off
3. washwashed twice with water
4. dry with materialdried with sodium sulfate
5. customevaporated
6. washThe residue is washed with pentane
7. customrecrystallized from cyclohexane