Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 275209Generated: October 31, 2026

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid → HCID 20089993, compound

https://huagongshe.com/reaction/275209

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acidHCID 5210422—
Reactanttert-Butyl 3-azabicyclo[4.1.0]heptan-1-ylcarbamateHCID 20089946—
ProductHCID 20089993HCID 2008999365%

Reaction Steps

According to the procedure of Example 34A, 1-tert-butoxycarbonylamino-3-azabicyclo[4.1.0]heptane (270.0 mg, 1.27 mmol) and 1-cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid (275.6 mg, 1.03 mmol were reacted to generate the title compound (304.2 mg, 0.666 mmol, 65%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05391763
Source datasetuspto-grants-1995_02
ORD IDord-70c8ea3b8d484486ab1944114be6b6ac
Source noteuspto-grants-1995_02