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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 275341Generated: October 26, 2026

rac-(1R,2R)-2-aminocyclopentan-1-ol → 2-(trans-2-Hydroxycyclopentylamino)-1,7-bis(phenylmethyl)purin-6-one

https://huagongshe.com/reaction/275341

Reaction equation

Participants

RoleNameHCIDCharge
Reactantrac-(1R,2R)-2-aminocyclopentan-1-olHCID 10464306—
Reactant2-Chloro-1,7-bis(phenylmethyl)purin-6-oneHCID 20087886—
Product2-(trans-2-Hydroxycyclopentylamino)-1,7-bis(phenylmethyl)purin-6-oneHCID 54255675—

Reaction Steps

Treat 2-chloro-1,7-bis(phenylmethyl)purin-6-one with trans-2-aminocyclopentanol as described in Preparative Example 5 to give the title compound, a tan solid. FAB MS: M+1=416.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05393755
Source datasetuspto-grants-1995_02
ORD IDord-0f9be29703234980a8e05c1bdd3b9ada
Source noteuspto-grants-1995_02