HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Cyanophenol → 4-(4-Acetyl-3-hydroxy-2-propylbenzyloxy)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Cyanophenol | HCID 13019 | — |
| Reactant | 4-Acetyl-3-hydroxy-2-propylbenzyl chloride | HCID 13781022 | — |
| Product | 4-(4-Acetyl-3-hydroxy-2-propylbenzyloxy)benzonitrile | HCID 13781030 | — |
Reaction Steps
The title nitrile intermediate was prepared from 18.12 g. of 4-acetyl-3-hydroxy-2-propylbenzyl chloride and 35.7 g. of 4-cyanophenol following the general procedure of Example 1. Crystallization from ethanol/water provided 19.0 g. of the desired intermediate, m.p. 102°-103° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05393768 |
| Source dataset | uspto-grants-1995_02 |
| ORD ID | ord-558d3a0e576f48e9963ab33921adee95 |
| Source note | uspto-grants-1995_02 |