Methyl isothiocyanate → HCID 15230793, compound

HRID 275534Notes

Reaction equation

HRID 275534 reaction equation
C([O:4][C:5]1[C:10]([C:11]([CH3:14])([CH3:13])[CH3:12])=[CH:9][C:8]([CH:15]([NH:17][OH:18])[CH3:16])=[CH:7][C:6]=1[C:19]([CH3:22])([CH3:21])[CH3:20])(=O)C.[CH3:23][N:24]=[C:25]=[S:26]>>[CH3:21][C:19]([C:6]1[CH:7]=[C:8]([CH:15]([N:17]([OH:18])[C:25]([NH:24][CH3:23])=[S:26])[CH3:16])[CH:9]=[C:10]([C:11]([CH3:13])([CH3:12])[CH3:14])[C:5]=1[OH:4])([CH3:22])[CH3:20]

Participants

3

Reactant 2

HCID 11167Methyl isothiocyanateHCID 54086794HCID 54086794, compound

Product 1

HCID 15230793HCID 15230793, compound

Procedure

To a solution of 0.500 g (0.0016 mole) of 2,6-bis (1,1-dimethylethyl) -4- [1- (hydroxyamino) ethyl ]phenol acetate is added 0.128 g (0.00175) of methyl isothiocyanate. The reaction mixture is stirred at room temperature for 18 hours and evaporated to near dryness. The residue is washed with Et2O and there is obtained 0. 300 g (55% ) white solid, m.p. 175°-175.5° C.

Workup

  1. customevaporated
  2. washThe residue is washed with Et2O
  3. customthere is obtained 0

Sources & evidence

ORD record
ord-76e9f681875b4693b9eaa541fe635cf8
Source dataset
uspto-grants-1995_02
Patent number
US05393923

Reaction notes

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