Potassium Persulfate → HCID 54305882, compound

HRID 275600Notes

Reaction equation

HRID 275600 reaction equation
[C:1]([NH:8][C@H:9]([C:12]([OH:14])=[O:13])[CH2:10]S)([O:3][C:4]([CH3:7])([CH3:6])[CH3:5])=[O:2].[CH2:15]([C:22](=[CH2:33])[C:23]([O:25][CH2:26][C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1)=[O:24])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1.[S:34]([O:38]OS([O-])(=O)=O)([O-])(=O)=[O:35].[K+].[K+]>>[CH2:26]([O:25][C:23]([CH:22]([CH2:15][C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1)[CH2:33][S:34]([CH2:10][C@@H:9]([C:12]([OH:14])=[O:13])[NH:8][C:1]([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])=[O:2])(=[O:38])=[O:35])=[O:24])[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1

Participants

4

Reactant 3

HCID 24412Potassium PersulfateHCID 152319N-tert-ButyloxycarbonylcysteineHCID 10912012Benzyl 2-Benzylacrylate

Product 1

HCID 54305882HCID 54305882, compound

Procedure

In an analogous manner to that described in Example 1, paragraphs (d) and g), by adding Boc-L-cysteine to benzyl 2-benzylacrylate and subsequently oxidizing with potassium monopersulphate triple salt there was obtained 3-[[(RS)-2-[(benzyloxy)carbonyl]-3-phenylpropyl]sulfonyl]-N-(tert-butoxycarbonyl)-L-alanine as a colourless oil, MS: 506 (M+H)+.

Sources & evidence

ORD record
ord-90e4b03509ed4aef9a323851f60386ae
Source dataset
uspto-grants-1995_02
Patent number
US05393875

Reaction notes

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