Cyclopropanecarbonyl chloride → HCID 67807673, compound

HRID 275610Notes

Reaction equation

HRID 275610 reaction equation
[CH:1]1([C:4](Cl)=[O:5])[CH2:3][CH2:2]1.[OH:7][CH2:8][C:9]([S:12]([CH2:15][CH:16]([CH2:27][C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)[C:17]([O:19][CH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=[O:18])(=[O:14])=[O:13])([CH3:11])[CH3:10]>N1C=CC=CC=1>[CH:1]1([C:4]([O:7][CH2:8][C:9]([S:12]([CH2:15][CH:16]([CH2:27][C:28]2[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=2)[C:17]([O:19][CH2:20][C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=2)=[O:18])(=[O:14])=[O:13])([CH3:11])[CH3:10])=[O:5])[CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 77637Cyclopropanecarbonyl chlorideHCID 54448487HCID 54448487, compound

Product 1

HCID 67807673HCID 67807673, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

In an analogous manner to that described in paragraph (d) above, by reacting cyclopropanecarbonyl chloride and benzyl rac-α-[[(2-hydroxy-1,1-dimethylethyl)sulfonyl]methyl]hydrocinnamate in pyridine there was obtained benzyl rac-[[[2-[(cyclopropylcarbonyl)oxy]-1,1-dimethylethyl]sulfonyl]methyl]hydrocinnamate as a colourless oil, MS: 367 (M-benzyl)+.

Sources & evidence

ORD record
ord-cd8dfc8f12ab4099a5842e3c9180b020
Source dataset
uspto-grants-1995_02
Patent number
US05393875

Reaction notes

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