反应详情

In an analogous manner to that described in Example 1, paragraph (c), by the condensation of Fmoc-His(Fmoc)-OH and (1S,2R,3S)-3-amino-1-cyclopropyl-4-phenyl-1,2-butanediol followed by cleavage of the protecting groups using piperidine in methylene chloride there was obtained (S)-α-amino-N-[(1S,2R,3S)-1-benzyl-3-cyclopropyl-2,3-dihydroxypropyl]-imidazole-4-propionamide as a colourless foam, MS: 359 (M+H)+.