HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2,3,4-Tetrahydroisoquinoline → HCID 18315702, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2,3,4-Tetrahydroisoquinoline | HCID 7046 | — |
| Reactant | 5,6-Dimethyl-2-(4-methylthiazol-2-yl)amino-4-chloropyrimidine | HCID 18315685 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 18315702 | HCID 18315702 | 10.8% |
Reaction Steps
The same procedures as in Step 4 of Example 22 were repeated using 5,6-dimethyl-2-(4-methylthiazol-2-yl)amino-4-chloropyrimidine(0.85 g, 3.34 mmol), 1,2,3,4-tetrahydroisoquinoline(0.42 ml, 3.34 mmol) and dimethylformamide (5 ml) to afford 140 mg of the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06352993B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-00eae21235944d0ca312a6bf37e89a46 |
| Source note | uspto-grants-2002_03 |