HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 18315658, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2,4-Dichloro-5,6-dimethylpyrimidine | HCID 241553 | — |
| Reactant | HCID 18315710 | HCID 18315710 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 18315658 | HCID 18315658 | 72.9% |
Reaction Steps
After 5,8-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline(10 g, 4.82 mmol) and triethylamine (0.67 ml, 4.82 mmol) were added to a suspension of 5,6-dimethyl-2,4-dichloropyrimidine(0.71 g, 4.02 mmol) in dimethylformamide, 1.02 g of the titled compound was obtained in accordance with the same procedure as in Step 1 of Example 35. (Yield: 72.8%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06352993B1 |
| Source dataset | uspto-grants-2002_03 |
| ORD ID | ord-34f82632a800436688aa009e0b5e3aba |
| Source note | uspto-grants-2002_03 |