Triethylamine → HCID 18315771, compound

Participants

Reaction Steps

After 4-fluoroaniline(0.40 ml, 4.13 mmol) and triethylamine(0.58 ml, 4.13 mmol) were added to a solution of 5,6-dimethyl-2-chloro-4-(5,8-dimethoxy-1-methyl-1,2,3,4tetrahydroisoquinolin-2-yl)pyrimidine (1.0 g, 2.87 mmol) in dimethylformamide(5 ml), 0.67 g of the titled compound was obtained in accordance with the same procedure as in Step 2 of Example 25. (Yield: 51.2%)

Provenance & Evidence