HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 276076Generated: October 25, 2026
Thionyl Chloride → 1-(Chloromethyl)-4-phenoxybenzene
https://huagongshe.com/reaction/276076
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | (4-Phenoxyphenyl)methanol | HCID 826195 | — |
| Product | 1-(Chloromethyl)-4-phenoxybenzene | HCID 520994 | 97.2% |
Reaction Steps
Thionyl chloride (13.34 g) was added to 4.06 g of 4-phenoxybenzyl alcohol, and the mixture was stirred at 80° C. for 3.5 hours. After the completion of the concentration, the reaction mixture was extracted with ethyl acetate and with water. The organic layer was concentrated to give 4.31 g of 4-phenoxybenzyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06352985B1 |
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| Source dataset | uspto-grants-2002_03 |
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| ORD ID | ord-e48630886bf3471b8d19ba088efbd56b |
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| Source note | uspto-grants-2002_03 |
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