1-Butanol → HCID 86757831, compound

Participants

Reaction Steps

A solution of Compound 9 (541 mg, 1.45 mmol) in 3N aqueous hydrochloric acid (100 mL) was warmed until solution became clear and then stirred at room temperature. After 10 hours, n-butanol was added and the solution was evaporated. The residue was chromatographed on a flash column with CHCl3—MeOH (4:1) to give 0.244 g of Compound 9a in 82 percent yield.

Provenance & Evidence